Abstract #0335
Fast B1-insensitive T2 relaxometry of the human brain at high to ultra-high fields
Rahel Heule 1 , Peter Br 2 , Christian Mirkes 3,4 , Klaus Scheffler 3,4 , Siegfried Trattnig 2 , and Oliver Bieri 1
1
Division of Radiological Physics, Department
of Radiology, University of Basel Hospital, Basel,
Switzerland,
2
MR
Centre of Excellence, Department of Biomedical Imaging
and Image-guided Therapy, Medical University of Vienna,
Vienna, Austria,
3
MRC
Department, Max Planck Institute for Biological
Cybernetics, Tbingen, Germany,
4
Department
of Biomedical Magnetic Resonance, University of Tbingen,
Tbingen, Germany
Quantitative imaging at high to ultra-high fields
suffers from prominent B1 field inhomogeneities that
affect quantification accuracy. Recently, a 3D triple
echo steady-state (TESS) approach has been presented
that offers fast B1-insensitive T2 quantification. In
this work, the sensitivity to subject motion of 3D-TESS
is reduced by investigating a rapid 2D technique suited
for brain applications. The feasibility and reliability
of 2D TESS-T2 relaxometry is demonstrated in human brain
scans at high (3 T) and ultra-high (7 T and 9.4 T)
fields. The results accentuate the potential of TESS-T2
to act as valuable measure for the detection of brain
tissue alterations.
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