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Abstract #0302

Comparison of Quantitative T 2 Mapping Techniques for Articular Cartilage

Stephen J. Matzat 1 , Emily J. McWalter 1 , Feliks Kogan 1 , Weitian Chen 2 , and Garry E. Gold 1,3

1 Radiology, Stanford University, Stanford, CA, United States, 2 MR Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States, 3 Bioengineering, Stanford University, Stanford, CA, United States

New MR pulse sequences provide faster methods for T 2 mapping of articular cartilage, yet each method may introduce a bias in T 2 quantitation. The present study analyzes quantitative outcomes from six MR sequences for in vivo T 2 mapping of patellar, femoral, and tibial cartilage, using single echo spin echo as a reference standard. Some sequences exhibited a consistent bias in T 2 measurements while others demonstrated varied bias along the range of T 2 values. Overall variation between sequences was appreciable and highlights the importance of further study of these differences.

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