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Abstract #0270

Global tractography of multi-shell HARDI data

Daan Christiaens 1,2 , Frederik Maes 1,2 , Stefan Sunaert 1,3 , and Paul Suetens 1,2

1 Medical Imaging Research Center, KU Leuven, Leuven, Vlaams-Brabant, Belgium, 2 Electrical Engineering, KU Leuven, Leuven, Vlaams-Brabant, Belgium, 3 Translational MRI, KU Leuven, Leuven, Vlaams-Brabant, Belgium

We extend the global fibre reconstruction framework of Reisert et al. (2011) for multi-shell HARDI data and allow to use any fibre response function represented in spherical harmonics. Additionally, we introduce two isotropic terms that model the fractions of grey matter and cerebrospinal fluid. Our approach successfully recovers the main white matter tracts on the high-resolution, multi-shell data of the human connectome project, using a fibre response function estimated from the data.

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