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Abstract #0263

Comparison of 3D UTE- and CT-Based Phase Aberration Correction for Transcranial MR-Guided Focused Ultrasound Surgery

Urvi Vyas 1 , Ethan M Johnson 2 , John Pauly 2 , and Kim Butts Pauly 1,3

1 Radiology, Stanford University, Palo Alto, CA, United States, 2 Electrical Engineering, Stanford University, Palo Alto, CA, United States, 3 Bioengineering, Stanford University, CA, United States

CT-based imaging is currently used in transcranial MR-guided focused ultrasound surgery to correct for distortions in the location and shape of the beams focus due to heterogeneities of the cranium In this work, we compare bone contours segmented from CT and 3D UTE images. We use 3D ultrasound beam simulations to demonstrate the effect on the location and intensity of the focal zone using phase aberrations calculated from a cortical-only CT model and a UTE bone model. We find that correcting phase aberrations using the UTE model recovers 75% of the focal intensity at the focal (compared to the cortical CT model recovering 98%).

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