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Abstract #0215

Quantification of CBF Changes in the Human Brain During Moderate Exercise With pCASL

Nuno A da Silva 1 , Ke Zhang 1 , Pavel Chervakov 1 , Eleonora Maggioni 1,2 , Thomas W Okell 3 , and N Jon Shah 1,4

1 Forschungszentrum Jlich GmbH, Institute of Neuroscience and Medicine - 4, Jlich, Germany, 2 Politecnico di Milano, Milano, Italy, 3 Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 4 RWTH Aachen, Department of Neurology, Aachen, Germany

In this study we investigate the effect of moderate exercise on brain cerebral blood flow (CBF) using arterial spin labeling (ASL) measurements. A dedicated setup with an ergometer pedal platform in the MR-BrainPET scanner was utilised. We demonstrated that with this setup and by measuring with pseudo-continuous arterial spin labeling (pCASL), the variations of CBF in a healthy brain during exercise and following exercise can be detected and evaluated.

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