Abstract #0079
Age-dependent diffusion and perfusion normal values in gray matter brain structures in children
Nils Daniel Forkert 1 , Zhaoying Han 1 , Matthew Daniel Li 1 , Roland Bammer 1 , and Kristen Yeom 1
1
Department of Radiology, Stanford
University, Stanford, CA, United States
The extraction of diffusion and perfusion parameters
from MRI is of high clinical utility in various
neurological diseases. However, adult normal values
cannot be applied directly to pediatric patients due to
age-dependent parameter changes. The aim of this work is
to investigate the age-dependent change of ADC and CBF
values in healthy children over the entire pediatric age
range by applying an atlas-based analysis of ASL and ADC
datasets in different brain regions. Overall,
logarithmic relations between age and ADC as well as CBF
values were found, which may help to identify
neuropathological conditions of childhood in future.
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