Abstract #0005
In-vivo Mapping of transcranial Direct Current Stimulation(tDCS) of Human Brain using MRI
Mayank V Jog 1 , Robert Smith 2 , Kay Jann 2 , Walter Dunn 3 , Allan Wu 2 , and Danny JJ Wang 2
1
Biomedical Engineering, University of
California Los Angeles, Los Angeles, California, United
States,
2
Neurology,
University of California Los Angeles, Los Angeles,
California, United States,
3
Psychiatry,
University of California Los Angeles, Los Angeles,
California, United States
Transcranial Direct Current Stimulation (tDCS) is a
neuromodulation technique shown to have applications in
stroke, pain-relief and cognition. tDCS is attractive as
a treatment modality since it involves low currents and
basic electrode placement on the surface of the head. To
date, only mathematical modeling has been used to study
tDCS-induced currents on the brain. We used MRI field
mapping for in-vivo visualization of tDCS-induced
electric currents (Basis: Amperes law). Utilizing
concurrent tDCS-MRI with a Real/Sham paradigm, we
observed significant magnetic field or phase changes in
the brain parenchyma providing imaging evidence that
tDCS effects do penetrate inside the brain.
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